Data Utilization


While the PROPEL reagents are a limited resource, the long-term value of the project lies in the data, methods and software generated within the project. The data generated thus far is immediately valuable for validating experimental MS/MS data for human proteins, particularly in cases where the analytical evidence is sparse (such as single peptide IDs etc). The data can also be used to build MRM/SRM/PRM assays as well as to construct spectrum libraries for data independent acquisition methods (DIA). The ProteomeTools project will release such libraries in due course (PROSPECT – ProteomeTools Spectrum Compendium). The data may also serve as training sets for numerous bioinformatic applications such as the development of software tools that may include intelligent data acquisition routines within the instrument control software or the development of more powerful database or spectral library search engines utilizing e.g. concepts of machine learning.